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BTC — EGF
Pathways - manually collected, often from reviews:
-
Reactome Reaction:
BTC
→
EGF
(reaction)
Vijapurkar et al., Exp Cell Res 2003, Walton et al., J Biol Chem 1990, Li et al., Cell Signal 2007, Xu et al., Mol Cell Biol 2007, Hazan et al., Cell Growth Differ 1990, Kaushansky et al., Chem Biol 2008, Helin et al., J Biol Chem 1991, Margolis et al., J Biol Chem 1989, Ricci et al., Oncogene 1995, Wallasch et al., EMBO J 1995, Prigent et al., EMBO J 1994, Soler et al., Oncogene 1994, Segatto et al., Oncogene 1993, Cohen et al., J Biol Chem 1996, Pinkas-Kramarski et al., EMBO J 1996
-
Reactome Reaction:
BTC
→
EGF
(indirect_complex)
Cohen et al., J Biol Chem 1996
Text-mined interactions from Literome
Kim et al., FASEB J 2003
(Neovascularization, Pathologic) :
Betacellulin (BTC) is a member of the epidermal growth factor (EGF) family, and it
acts through
EGF receptors
Mifune et al., Am J Physiol Cell Physiol 2004
:
We found that
BTC stimulated phosphorylation of
EGF receptor (EGFR) at Tyr1068, which was completely blocked by an EGFR kinase inhibitor, AG-1478
Yasuda et al., J Vet Med Sci 2007
:
These results suggest that
EGF , betacellulin, and activin A promote pancreatic cell proliferation, islet B-cell differentiation, and islet B-cell differentiation and functional maturation, respectively, and that EGF,
betacellulin , and activin A, in this order,
regulate islet B-cell neogenesis
Tse et al., Comp Biochem Physiol A Mol Integr Physiol 2009
:
Differential
regulation of
betacellulin and heparin binding EGF-like growth factor in cultured zebrafish ovarian follicle cells by
EGF family ligands
Taylor et al., Proc Natl Acad Sci U S A 1999
:
However, relative levels of
EGF receptor tyrosine phosphorylation stimulated by epiregulin were less than those
induced by EGF or
betacellulin