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EGF — IGFBP4

Text-mined interactions from Literome

Grimes et al., Endocrinology 1992 : However, in the presence of epidermal growth factor ( which was without independent effect on the 30-kDa IGFBP ), insulin also induced this 30-kDa IGFBP
Barreca et al., Mol Cell Endocrinol 1992 : The stimulation of IGF-I and IGFBP secretion by EGF appears to be dose dependent with a significant increment already evident at 5 nM
Nuttinck et al., Domest Anim Endocrinol 2004 : Under defined culture conditions, IGFBP-2 and FSHR mRNA expression remained at a high level in TCM199 alone and were significantly reduced ( P < 0.05 ) in the presence of 10 ng/ml EGF after a 24 h period of in vitro maturation
Mondschein et al., Endocrinology 1990 : In contrast, IGFBP-3 levels were enhanced by epidermal growth factor
Corps et al., Endocrinology 1991 : Production of this IGFBP by Swiss 3T3 cells was stimulated by 50-150 % by the mitogens bombesin, vasopressin, platelet derived growth factor, epidermal growth factor , and 12-O-tetradecanoylphorbol 13-acetate and also by IGF-I
Oguchi et al., Am J Physiol 1994 : IGF-I stimulated mainly IGF-BP-3 production, but epidermal growth factor (EGF) and transforming growth factor-alpha ( TGF-alpha ) stimulated predominantly IGF-BP-4 secretion
Bachrach et al., Growth Regul 1995 (Adenocarcinoma, Follicular...) : IGFBP-4 production was increased in the presence of TSH, forskolin, and EGF and was reduced by TPA
Oguchi et al., Zhonghua Min Guo Xiao Er Ke Yi Xue Hui Za Zhi 1997 : IGF-I stimulated mainly IGFBP-3 production, while EGF stimulated predominantly IGFBP-4 ... The effects of IGF-I and EGF on IGFBP secretion diminished with increasing cell differentiation
Price et al., Am J Respir Cell Mol Biol 1999 : In 48-h coincubation experiments, EGF in combination with PDGF-BB or with bFGF, and bFGF in combination with PDGF-BB, resulted in IGFBP-4 accumulations twice that expected from a summation of the effects of either growth factor alone ( IGFBP-4 increased 9.8-, 4.0-, and 1.8-fold by PDGF-BB, EGF, and bFGF, respectively ; and 27.1-, 37.3-, and 13.0-fold by PDGF-BB plus EGF, PDGF-BB plus bFGF, and EGF plus bFGF, respectively )