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GP9 — PRKCA

Text-mined interactions from Literome

Lee et al., Cancer Chemother Pharmacol 2004 : As expected, SNL glycoprotein dose-dependently inhibited PKCalpha translocation, NF-kappaB DNA binding activity, NF-kappaB protein activity and NO production in HCT-116 cells stimulated with TPA ( 61.68 ng/ml, 100 nM )
Zhan et al., J Biol Chem 2005 (Neovascularization, Pathologic) : Transcriptional repression of protein kinase Calpha via Sp1 by wild type p53 is involved in inhibition of multidrug resistance 1 P-glycoprotein phosphorylation
Heo et al., J Med Food 2005 : The results in this study indicated that SNL glycoprotein induces apoptosis through modulation of PKCalpha and NF-kappaB activity in MCF-7 cells
Lim et al., J Med Food 2005 : Taken together, the results of this study showed that the activation of PKCalpha , NF-kappaB, and Bax expression by SNL glycoprotein is possibly involved in the apoptotic process
Oh et al., Biol Pharm Bull 2007 : The results in the present study showed that RVS glycoprotein ( 200 microg/ml ) inhibits ROS production and PKCalpha translocation, and down-regulates the expression of NF-kappaB and AP-1
Lee et al., J Nutr Biochem 2009 : In the G/GO or HX/XO stimulated protein kinases activity, ZPDC glycoprotein inhibited translocation of protein kinase C alpha (PKCalpha) to membrane and phosphorylation of extracellular signal regulated kinase, p38 MAP kinase and c-Jun N-terminal kinase, respectively
Lee et al., Mol Cell Biochem 2008 : Our results showed that the DBD glycoprotein significantly inhibits the translocation of protein kinase C alpha (PKCalpha) to membrane and the phosphorylation of extracellular signal regulated kinase ( ERK ) in LPS stimulated RAW 264.7 cells
Blobe et al., J Biol Chem 1993 (Breast Neoplasms) : These changes paralleled the increases in P-glycoprotein pump function and the MDR phenotype underscoring the role for PKC alpha in regulating P-glycoprotein phosphorylation and function