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TP53 — TRAF4
Text-mined interactions from Literome
Sax et al., J Biol Chem 2003
:
TRAF4 is specifically regulated by p53 in
response to temperature sensitive p53, overexpression of
p53 by use of an adenovirus, and stabilization of p53 in response to DNA damage
Gu et al., Cancer Biol Ther 2007
(Carcinoma, Squamous Cell...) :
Endogenous p63 bound to the TRAF4 promoter in vivo and reporter assays showed that p63, p73 and
p53 can all
transactivate TRAF4 , with TAp63 isoforms being the most potent activators