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FAS — IL1A

Text-mined interactions from Literome

Schelling et al., Kidney Int 1999 (Atrophy...) : These data are supported by in vitro studies that showed that interleukin-1alpha or tumor necrosis factor-alpha, cytokines that are secreted in chronic renal failure, stimulated increases in Fas expression in cultured RTCs ... Both murine kidney cortex and RTCs in culture demonstrated constitutive expression of Fas ligand, a feature that is characteristically restricted to lymphocytes and immune privileged tissues and previously unrecognized in RTCs. Functional studies revealed that interleukin-1alpha stimulated RTC Fas expression was accompanied by increased apoptosis, which was inhibited by blocking anti-Fas ligand antibodies
Klein et al., Hum Gene Ther 2000 (Insulinoma) : Like pancreatic beta cells, betaTC-3 cells do not constitutively express Fas , but Fas expression can be induced with IL-1 and IFN-gamma
Rescigno et al., J Exp Med 2000 (Inflammation) : Fas engagement induces the maturation of dendritic cells (DCs), the release of interleukin (IL)-1beta , and the production of interferon gamma in the absence of IL-12 during DC-T cell cognate interaction : a new role for Fas ligand in inflammatory responses
Wachlin et al., J Autoimmun 2003 (Diabetes Mellitus, Type 1) : However, IL-1beta induced Fas expression was significantly enhanced only on beta-cells from diabetes-prone BB rats
Schaub et al., Circ Res 2003 : These data suggest that calpains play a dominant role in Fas/FADD induced IL-1alpha release and MCP-1 upregulation and that caspase activation may function to amplify the effects of calpain activation
Thomas et al., Diabetes 2004 (Diabetes Mellitus, Type 1...) : IL-1 action was not required for induction of class I major histocompatibility complex or Fas by TNF and IFN-gamma
Kondo et al., Immunology 2009 (Myositis) : In vitro culturing of muscle cells with the proinflammatory cytokines interferon-gamma, tumour necrosis factor-alpha, and interleukin (IL)-1beta synergistically increased Fas expression, susceptibility to Fas mediated apoptosis, and the expression of cytoplasmic caspases 8 and 3
Bossaller et al., J Immunol 2012 : However, the mechanisms by which Fas regulates IL-1ß activation remain unresolved
Uchiyama et al., J Immunol 2013 (Inflammation...) : However, the role of Fas mediated production of proinflammatory cytokines such as IL-18 and IL-1ß in bacterial infection is unclear
Fukuo et al., Gerontology 1997 (Arteriosclerosis...) : However, coincubation with NG-monomethyl-L-arginine, an inhibitor of nitric oxide ( NO ) synthesis, inhibited the upregulation of Fas induced by IL-1 and TNF-alpha
Mohan et al., Exp Eye Res 1997 : Specifically, these experiments examined ( 1 ) the effect of genetic inactivation of Fas or Fas ligand genes on keratocyte apoptosis in response to corneal epithelial wounding, ( 2 ) whether cultured human corneal epithelial and endothelial cells are competent to undergo apoptosis in response to Fas activation, ( 3 ) expression of membrane bound and soluble Fas and Fas ligand in corneal cells, and ( 4 ) the effect of IL-1 on expression of Fas and Fas ligand in corneal fibroblasts
Schelling et al., Lab Invest 1998 (Kidney Failure, Chronic) : These data are supported by in vitro studies showing that interleukin-1alpha and tumor necrosis factor-alpha, cytokines secreted in chronic renal failure, stimulated increases in Fas expression in cultured RTC ... Functional studies revealed that interleukin-1alpha stimulated RTC Fas expression was accompanied by increased apoptosis, which was inhibited by blocking anti-Fas ligand antibodies
Choi et al., J Immunol 1999 : Our data demonstrated that : 1 ) FasL is expressed constitutively on astrocytes taken from a fetus or an adult and that its expression increases when these cells are treated with IL-1, IL-6, or TNF-alpha in which the pretreatment of IFN-gamma triggers astrocytes to express more FasL ; 2 ) astrocytes induce apoptosis in MOLT-4 cells through FasL ; 3 ) Fas is also expressed constitutively and is up-regulated by IL-1 , IL-6, or TNF-alpha in which the pretreatment of IFN-gamma triggers astrocytes to express more Fas ; 4 ) apoptosis occurs when fetal astrocytes are treated with agonistic anti-Fas IgM Ab after culture with IFN-gamma and TNF-alpha ; and 5 ) TNF related apoptosis inducing ligand is up-regulated in fetal astrocytes with stimuli of IL-1 or TNF-alpha