Gene interactions and pathways from curated databases and text-mining

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ERBB2 — MMP9

Text-mined interactions from Literome

Ke et al., Int J Cancer 2006 : By gelatin zymography, we showed that over-expression of ErbB2 increased the production of matrix metalloproteinase-2 (MMP-2) and MMP-9 in human mammary epithelial cells ( HB2 )
Kim et al., Cancer Lett 2009 (MAP Kinase Signaling System...) : Using pharmacological inhibitors, we further show that p38 MAPK and Akt signaling pathways are crucial for the ErbB2 induced MMP-9 up-regulation, invasion and migration of MCF10A cells