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TCF12 — TXN
Protein-Protein interactions - manually collected from original source literature:
Studies that report less than 10 interactions are marked with *
Text-mined interactions from Literome
Wei et al., Cancer Res 2000
:
Thioredoxin nuclear translocation and interaction with redox factor-1
activates the activator protein-1
transcription factor in response to ionizing radiation
Li et al., Cell Signal 2005
:
Taken together, it was implicated that the oxidizing equivalents might flow from HPO to TRX and then to substrate protein by the dimerization of HPO, and its interaction with
TRX finally
activates the redox-sensitive
transcription factor , suggesting a new redox signal pathway conducted by thiol-disulfide transformation in eukaryocytic cytoplasm
Song et al., Stem Cells Dev 2011
:
Overexpression of TRX1 and
TRX2 increased ERK1/2 phosphorylation, nuclear factor-kappaB activation, and
ß-catenin/Tcf promoter activities and inhibited lucine zipper tumor suppressor 2 expression