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BMP4 — TRPC3

Text-mined interactions from Literome

Lu et al., Am J Physiol Cell Physiol 2010 (Calcium Signaling...) : In this study, we investigated the effect of BMP4 on expression of TRPC and store operated Ca ( 2+ ) entry ( SOCE ) in pulmonary arterial smooth muscle cells ( PASMCs )
Zhang et al., Am J Physiol Cell Physiol 2013 (Calcium Signaling) : We previously demonstrated that BMP4 upregulates the expression of canonical transient receptor potential channel ( TRPC ) proteins and, thereby, enhances store operated Ca ( 2+ ) entry ( SOCE ) and elevates intracellular Ca ( 2+ ) concentration ( [ Ca ( 2+ ) ] i ) in pulmonary arterial smooth muscle cells ( PASMCs )
Li et al., Am J Respir Cell Mol Biol 2013 (Calcium Signaling...) : The present study investigated the signaling pathways through which BMP4 regulates TRPC expression and basal [ Ca ( 2+ ) ] i in distal PASMCs ... Real-time quantitative PCR was used for the measurement of mRNA, Western blotting was used for the measurement of protein, and fluorescent microscopic for [ Ca ( 2+ ) ] i was used to determine the involvement of p38 and extracellular regulated kinase (ERK)-1/2 mitogen activated protein kinase ( MAPK ) signaling in BMP4 induced TRPC expression and the elevation of [ Ca ( 2+ ) ] i in PASMCs