Pathways - manually collected, often from reviews:
OpenBEL Selventa BEL large corpus:
IRS1
→
ITGB1
(increases)
Evidence: Recently, b1 integrins have also been reported to enhance IRS-1 phosphorylation and interaction, but not glucose transport, with downstream molecules such as PI3-kinase and Akt (74). These results suggest that integrins and insulin/IGF-1 receptor signaling pathways converge at an early point in the signaling cascade around the IRS proteins.