Deng et al., Hum Mol Genet 2007
(Rett Syndrome) :
MeCP2 represses Fxyd1 transcription through direct interactions with sequences in the Fxyd1 promoter that are methylated in FC neurons
Banine et al., J Neurosci Res 2011
:
Fxyd1 expression is repressed by methyl CpG binding protein 2 (Mecp2) in the frontal cortex ( FC ) but not in the cerebellum ( CB ) of the mouse brain
Matagne et al., Brain Res 2013
(Body Weight...) :
To test the hypothesis that some of the behavioral phenotypes seen in these Mecp2 mutants could be ameliorated by genetically preventing the Fxyd1 response to MECP2 deficiency, we crossed Fxyd1 null male mice with Mecp2 ( 308 ) heterozygous females and behaviorally tested the adult male offspring