Hilmi et al., J Invest Dermatol 2008
(Melanoma) :
Accordingly, IGF1 increases the mRNA levels and protein expression of antiapoptotic members of the BCL2 family -- BCL2 and BCL-X ( L ) -- and that of the inhibitor of apoptosis protein, survivin
Singh et al., Growth Factors 2008
(Breast Neoplasms) :
Furthermore, IGF-II differentially regulated the intracellular translocation of Bcl-2 and Bcl-X ( L ), a critical process in breast cancer progression to hormone-independence
Singleton et al., J Biol Chem 1996
:
Finally, increased neuronal IGF-IR expression enhances the negative death regulator Bcl-xL