Aihara et al., Respiration 2000
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We investigated the effects of NAC and AMB on secretions of IL-12 and IL-10 from human alveolar macrophages ... Both NAC and AMB enhanced LPS induced secretion of IL-12 ... The ratio IL-12/IL-10 secretion was increased by AMB, but NAC did not affect it
Mazzeo et al., Cytokine 2002
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We thus studied the effect of reduced glutathione ( GSH ) and N-acetyl-cysteine (NAC) on IL-12 p75 production by human THP-1 cell stimulated with IFN-gamma and Staphylococcus aureus Cowan strain I ( SAC ), using ELISAs specific for IL-12 p75 or the p40 subunit