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ANXA6 — IL4

Text-mined interactions from Literome

Giallourakis et al., J Biol Chem 2000 : However, no differential activation of STAT6, Akt, IRS-2, or p70 ( S6k ), in response to IL-4 , was observed in these cells
Lutz et al., J Immunol 2002 : In contrast, the production of IL-12 p70 , but not IL-10 and TNF, induced by microbial products was enhanced only by IL-4 , not by IL-13 or Y119D, a selective type II IL-4R agonist, in vitro and in vivo
Tsunetsugu-Yokota et al., J Virol 2003 : The uptake of yeast VLPs induced DC maturation and enhanced cytokine production, notably, interleukin-12 p70
Temblay et al., J Allergy Clin Immunol 2007 (Food Hypersensitivity) : Peyer patch-DCs but not splenic DCs from sensitized C3H/HeJ but not Balb/c mice produced less IL-4 dependent IL-12p70 ... In vivo data confirmed this was restricted to the gut immune system, and it was not linked to reduced expression of IL-4 receptor or the lack of functional Toll-like receptor 4 ; instead, IL-4 failed to inhibit IL-10 production by PP-DCs, a pathway critically involved in IL-4 dependent production of IL-12p70
Lamhamedi-Cherradi et al., J Immunol 2008 (Respiratory Hypersensitivity) : Exogenous IL-12p70 added to cocultures of DCs and T cells resulted in reduced IL-4 and increased IFN-gamma expression when DCs were activated with AP