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TLR3 — TLR9

Text-mined interactions from Literome

An et al., Immunology 2002 : While inhibition of extracellular signal related kinase and NF-kappaB activation suppressed the up-regulation of the expression of TLR2, TLR4 and TLR9 mRNA, inhibition of p38 kinase prevented the up-regulation of TLR2 and TLR4 mRNA expression but enhanced the up-regulation of TLR9 expression
Coccia et al., Eur J Immunol 2004 : TLR-9 stimulation by CpG DNA induced the expression of all IFN-alpha, -beta, -omicron and -lambda subtypes in pDC, whereas TLR-4 stimulation by LPS, or TLR-3 stimulation by poly I:C, induced only IFN-beta and IFN-lambda gene expression in MDDC
Harii et al., Mol Endocrinol 2005 (Thyroiditis, Autoimmune...) : We conclude that functional TLR3 are present on thyrocytes ; TLR3 downstream signals can be overexpressed by pathogen related stimuli ; overexpression can be reversed by phenylmethimazole to a significantly greater extent than MMI by inhibiting only the IFN regulatory factor-3/IFN-beta/signal transducers and activation of transcription arm of the TLR3 signal system ; and TLR3 overexpression can induce an innate immune response in thyrocytes, which may be important in the pathogenesis of Hashimoto 's thyroiditis and in the immune cell infiltrates
Duez et al., Eur J Dermatol 2006 (Asthma...) : During the allergic reaction, TLR engagement on DC directs the polarization of the T cell response and, while TLR2 and TLR4 may favour both Th1 and Th2 responses, TLR9 induces the development of regulatory T cells
Sel et al., J Immunol 2007 (Asthma...) : These data indicate that TLR-3 or TLR-7 activation by viral TLR ligands has both preventive as well as suppressive effects on experimental asthma which is mediated by the additive effects of IL-12 and IL-10
van de Veerdonk et al., Immunobiology 2008 (Candidiasis) : In conclusion, TLR9 is a pathogen-recognition receptor for C. albicans, and TLR9 is involved in the induction of cytokines in response to C. albicans
Kim et al., FEMS Microbiol Lett 2012 (Inflammation) : L. plantarum genomic DNA mediated inhibition of signaling pathway and tumor necrosis factor-alpha was accompanied by the suppression of toll-like receptor (TLR) 2, TLR4, and TLR9 and the induction of interleukin-1 receptor associated kinase M, a negative regulator of TLR
Kwissa et al., Blood 2012 : In the draining lymph nodes ( LNs ), consistent with the effects in blood, all TLR-Ls induced expansion of CD14 ( + ) monocytes, but only TLR7/8-L and TLR9-L expanded the activated CD14 ( + ) CD16 ( + ) cells
Raicevic et al., Tissue Eng Part A 2012 : Inflammation was mimicked by a cytokine cocktail, and TLR activation was induced through TLR3 and TLR4 ligation
Melkamu et al., Journal of cell communication and signaling 2013 : These findings demonstrate that TLR3 activation differentially regulates TLR expression through autocrine signaling involving IL-6 secretion, IL-6Ra activation and subsequent phosphorylation of Stat3
Zhao et al., Fish Shellfish Immunol 2013 (Ciliophora Infections...) : TLR9 was induced in the skin and gill, whereas TLR21 was induced in the head kidney and spleen after infection