Gene interactions and pathways from curated databases and text-mining

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NOX4 — PTPN1

Text-mined interactions from Literome

Chen et al., J Cell Biol 2008 : ER localization of Nox4 is critical for the regulation of protein tyrosine phosphatase (PTP) 1B , also an ER resident, through redox mediated signaling
Ortiz et al., J Biol Chem 2012 : In addition, lack of PTP1B promoted an altered NADPH oxidase ( NOX ) expression pattern in response to TGF-ß, strongly increasing the NOX1/NOX4 ratio, which was reverted by genistein and p65 knockdown