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AGTR1 — NOS3
Protein-Protein interactions - manually collected from original source literature:
Studies that report less than 10 interactions are marked with *
Text-mined interactions from Literome
Kiss et al., Endocr Regul 2001
:
Changes in angiotensin
AT1 receptor mRNA levels in the rat brain after immobilization stress and inhibition of central
nitric oxide synthase
Ritter et al., FASEB J 2003
:
Inhibition of the
AT1-receptor did not
reduce AngII mediated
eNOS protein expression, whereas AT2 stimulation increased it 2.4-fold and AT2 inhibition suppressed it
Suzuki et al., Endocrinology 2006
(Hypertrophy) :
Activation of endothelial
nitric oxide synthase by the
angiotensin II type 1 receptor ... Although endothelial cells have been reported to express AngII type 1 (AT1) receptors, the exact
role of
AT1 in regulating
endothelial NO synthase (eNOS) activity remains unclear
Ratliff et al., Pediatr Nephrol 2007
:
Glomerular
eNOS gene expression during postnatal maturation and
AT1 receptor
inhibition ...
AT1X significantly
reduced NB
eNOS expression in both superficial, 90+/-10 %, and juxtamedullary glomeruli, 89+/-5 % respectively
Dong et al., J Pharmacol Exp Ther 2011
(Hypertension...) :
High-salt loading in SHRSPs caused the reduction of cerebral blood flow (CBF), cerebral hypoxia, white matter lesions, glial activation,
AT1 receptor up-regulation, endothelial nitric-oxide synthase (eNOS) uncoupling, inducible
nitric-oxide synthase induction , and nitroxidative stress
Wang et al., Apoptosis 2012
:
Overexpression of
AT1R and AT2R markedly
increased IL-1ß ( AT2R > AT1R ), iNOS ( AT2R > AT1R ) and
eNOS expression
Nakayama et al., Blood Press Suppl 1994
:
Angiotensin II type 1 receptor mediated inhibition of cytokine stimulated inducible
nitric oxide synthase expression in vascular smooth muscle cells