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IRS1 — UBTF

Protein-Protein interactions - manually collected from original source literature:

Studies that report less than 10 interactions are marked with *

• IRef Biogrid Interaction: IRS1 — UBTF (physical association, affinity chromatography technology) Sun et al., Mol Endocrinol 2003*
• IRef Biogrid Interaction: IRS1 — UBTF (physical association, affinity chromatography technology) Dalmizrak et al., Cancer Res 2007*
• IRef Hprd Interaction: UBTF — IRS1 (in vivo) Sun et al., Mol Endocrinol 2003*
• IRef Ophid Interaction: IRS1 — UBTF (aggregation, interologs mapping) Brown et al., Bioinformatics 2005

Text-mined interactions from Literome

Wu et al., J Biol Chem 2005 : In myeloid cells ( but not in mouse embryo fibroblasts ) IRS-1 signaling stabilizes the levels of UBF1 protein
Sun et al., J Cell Physiol 2007 : Dual regulation of upstream binding factor 1 levels by IRS-1 and ERKs in IGF-1-receptor signaling ... Ectopic expression of insulin receptor substrate-1 (IRS-1) in these cells inhibits the down-regulation of UBF1 ... When ERKs signaling is defective, as in cells over expressing the insulin receptor (InR) or selected mutants of the IGF-1R, UBF1 is down-regulated, even in the presence of IRS-1