Strickland et al., FASEB J 1995
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In addition, LRP regulates the expression of plasmin activity by directly binding and mediating the cellular internalization of urokinase- and tissue-type plasminogen activators
Zhang et al., J Biol Chem 1998
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It has been suggested that through its ability to internalize these ligands, LRP/alpha2MR may regulate the expression of plasminogen activator activity on cell surfaces ; this hypothesis, however, has not been experimentally confirmed