Gene interactions and pathways from curated databases and text-mining

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PLG — SMAD1

Text-mined interactions from Literome

Itoh et al., J Biol Chem 2003 : Characterization of their signaling properties revealed that the two L45 loop mutants did not mediate Smad dependent transcriptional responses, TGF-beta induced growth inhibition, and fibronectin and plasminogen activator-1 production in R4-2 mink lung epithelial cells lacking functional ALK5 protein
O'Connor et al., Mol Cancer Res 2007 (Neoplasm Metastasis...) : Smad1/5/8 dependent inhibitor of DNA binding 1 expression and Smad2/3 dependent plasminogen activator inhibitor I expression both were decreased and were accompanied by decreased cell proliferation