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ETS1 — NPR1

Text-mined interactions from Literome

Kumar et al., Biosci Rep 2009 : The objective of the present study was to elucidate the mechanism by which Ets-1 [ Ets ( E twenty-six ) transformation-specific sequence ] contributes to the regulation of Npr1 gene transcription and expression ... Overexpression of Ets-1 enhanced significantly Npr1 mRNA levels, protein expression, GC activity and ANP stimulated intracellular accumulation of cGMP in transfected cells ... Collectively, the present study demonstrates that Npr1 gene transcription and GC activity of the receptor are critically controlled by Ets-1 in target cells
Kumar et al., Hypertension 2009 : Overexpression of Ets-1 and p300 in mouse mesangial cells increased Npr1 promoter activity by 12-fold, natriuretic peptide receptor-A mRNA levels by 5-fold, and ANP dependent intracellular accumulation of cGMP by 26-fold
Kumar et al., J Biol Chem 2010 : The present study was conducted to examine the interactive roles of all-trans retinoic acid ( ATRA ), Ets-1 , Sp1, and histone acetylation on the transcriptional regulation and function of the Npr1 gene