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ADCY5 — HTR1A

Text-mined interactions from Literome

Odagaki et al., Hokkaido Igaku Zasshi 1992 : On the other hand, 5-HT1A mediated inhibition of forskolin stimulated adenylate cyclase in rat hippocampal membranes was not altered by chronic treatment with lithium or antidepressants
Lisinicchia et al., Cell Signal 2003 : In contrast, the effects of short-term ( 2 h ) 5-HT1A receptor activation on subsequent adenylate cyclase activity have not been determined
Odagaki et al., Journal of neural transmission. General section 1991 : No alterations in the 5-HT1A mediated inhibition of forskolin stimulated adenylate cyclase activity in the hippocampal membranes from rats chronically treated with lithium or antidepressants ... In order to determine the relevance of 5-HT1A related signal transduction in the mode of action of lithium and antidepressants, the effects of long-term treatment with these drugs on the 5-HT1A mediated inhibition of forskolin stimulated adenylate cyclase activity were investigated in the rat hippocampal membranes
Okada et al., J Neurochem 1989 : IAP treatment reduced by 30-55 % the 5-HT1A agonist inhibition of adenylate cyclase activity via 5-HT1A receptors ... The data indicate that the inhibitory guanine nucleotide binding protein or Go ( a similar GTP binding protein of unknown function purified from brain ) mediates the 5-HT1A agonist inhibition of hippocampal adenylate cyclase
Sleight et al., Eur J Pharmacol 1988 : These data suggest that chronic nonselective and chronic MAO A inhibition causes a down-regulation of the 5-HT1A mediated inhibition of forskolin stimulated adenylate cyclase activity
Harrington et al., J Pharmacol Exp Ther 1994 : Exposure of HeLa cells stably expressing cloned human 5-hydroxytryptamine (5-HT)1A receptors ( HA7 cells ) to the agonist 8-hydroxy-2- ( di-N-propylamino ) -tetralin ( 8-OH-DPAT ) results in a loss of high-affinity binding sites and a desensitization of receptor-adenylate cyclase coupling, as measured by 5-HT1A mediated inhibition of forskolin stimulated adenylate cyclase activity