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DEDD — SMAD3

Protein-Protein interactions - manually collected from original source literature:

Studies that report less than 10 interactions are marked with *

• IRef Biogrid Interaction: SMAD3 — DEDD (direct interaction, two hybrid) Xue et al., FEBS Lett 2010*
• IRef Biogrid Interaction: SMAD3 — DEDD (direct interaction, pull down) Xue et al., FEBS Lett 2010*
• IRef Biogrid Interaction: SMAD3 — DEDD (physical association, affinity chromatography technology) Xue et al., FEBS Lett 2010*
• IRef Intact Interaction: SMAD3 — DEDD (physical association, anti bait coimmunoprecipitation) Xue et al., FEBS Lett 2010*

Text-mined interactions from Literome

Xue et al., FEBS Lett 2010 : DEDD negatively regulates transforming growth factor-beta1 signaling by interacting with Smad3
Hua et al., Yao Xue Xue Bao 2013 : These results suggested that DEDD inhibits the activity of Smad3 through its death-effector domain