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SPP1 — TNF

Text-mined interactions from Literome

Vann et al., J Biol Chem 2002 (Glioma) : Surprisingly, we found that, although C6 cells can secrete SPP , which is enhanced by TNF-alpha , treatment of C6 cells with exogenous SPP or dihydro-SPP had no affect on BH ( 4 ) biosynthesis
Renkl et al., Blood 2005 : OPN induces their Th1 promoting tumor necrosis factor alpha (TNF-alpha) and interleukin-12 (IL-12) secretion, and enhances their allostimulatory capacity
Serlin et al., J Cell Biochem 2006 : Our results demonstrate a potent and dramatic increase in osteopontin expression induced by interleukin-1beta (IL-1beta), whereas tumor necrosis factor-alpha , transforming growth factor-beta, and angiotensin II had minimal effect
Agnholt et al., Scand J Immunol 2007 (Crohn Disease) : The in vitro effect of OPN stimulation on T-cell IFN-gamma, TNF-alpha , and IL-10 production was measured ... OPN increased CD69 and CD25 expression and enhanced T-cell IFN-gamma and TNF-alpha production in a dose dependent fashion with higher levels in CD than in healthy controls ( HC ), but induced a concomitant higher IL-10 production in HC than CD
Lee et al., Life Sci 2007 : Butein blocks tumor necrosis factor alpha induced interleukin 8 and matrix metalloproteinase 7 production by inhibiting p38 kinase and osteopontin mediated signaling events in HT-29 cells
Wiwanitkit et al., Pediatrics international : official journal of the Japan Pediatric Society 2008 (Biliary Atresia) : Effect of interleukin-2 and tumor necrosis factor-alpha on osteopontin : molecular function and biological process ... A new gene ontology technology was used to predict the molecular function and biological process of the effect of IL-2 and TNF-alpha on OPN ... Using GoFigure server, the molecular function and biological process of the effect of IL-2 and TNF-alpha on OPN is predicted
Lu et al., Allergy 2009 (Nasal Polyps...) : On the contrary, OPN induced IFN-gamma, IL-4, IL-5, IL-13, IL-1beta, and TNF-alpha production in sinonasal mucosa
Lacey et al., Osteoarthritis Cartilage 2009 : However, only TNFalpha inhibited osteonectin and osteopontin mRNA expression and only IL-1beta reduced cell proliferation
Jin et al., Mol Cell Endocrinol 1990 : Besides IL-1 alpha, tumor necrosis factor alpha (TNF-alpha) , lipopolysaccharides (LPS) and 1 alpha,25-dihydroxyvitamin D3 ( 1 alpha,25 ( OH ) 2D3 ) increased the osteopontin mRNA expression in both the clonal osteoblasts ( MC3T3-E1 ) and the primary osteoblast-like cells
Buommino et al., Arch Dermatol Res 2012 (Psoriasis) : Moreover, OPN and MMP-9 were enhanced by TNF-a and down-regulated by anti-TNF-a treatment in healthy PBMC ... These findings may suggest that OPN and MMP-9 may be regulated by TNF-a , indicating a possible role in the pathogenesis of psoriasis
Sun et al., Cell Mol Immunol 2013 (Breast Neoplasms) : All OPN transcripts significantly inhibited TNF-a and enhanced IL-10 production by monocytes ... Using neutralizing antibody and recombinant cytokines, we found that OPN overexpressed by tumor cells regulates the production of TNF-a and IL-10 by monocytes partly via MCP-1 and TGF-ß1, respectively
Miyazaki et al., Ann N Y Acad Sci 1995 (Pulmonary Fibrosis) : Since OPN can be induced in macrophages by TNF-alpha stimulation and since on the other hand osteopontin appears to decrease the level of nitric oxide synthase, and thus the production of nitric oxide, osteopontin might also indirectly have an antifibrotic effect
Yang et al., Life Sci 1997 : Moreover, SPP had a significant effect on anti-DNP IgE induced histamine release or tumor necrosis factor-alpha production from RPMC
Lee et al., J Korean Med Sci 1998 : To investigate whether MCP-1, CINC, RANTES, osteopontin and ICAM-1 mRNA could be induced in cultured rat mesangial cells by interleukin-1beta(IL-1beta), tumor necrosis factor-alpha (TNF-alpha) and lipopolysaccharide (LPS), and whether MCP-1 and CINC gene expression could be modulated by dexamethasone, Northern blot assays were performed ... On the other hand, IL-1beta, TNF-alpha and LPS had little effect on osteopontin gene expression but fetal calf serum could increase osteopontin mRNA