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JAK1 — TCF23

Text-mined interactions from Literome

Miller et al., J Immunol 1999 : We demonstrate that HCMV inhibits IFN-alpha stimulated MHC class I, IFN regulatory factor-1, MxA and 2',5-oligoadenylate synthetase gene expression, transcription factor activation, and signaling in infected fibroblasts and endothelial cells by decreasing the expression of Janus kinase 1 and p48, two essential components of the IFN-alpha signal transduction pathway
Madden et al., J Immunol 2002 : Binding of IL-4 by either the type 1 or 2 IL-4R, or of IL-13 by the type 2 IL-4R, initiates Jak dependent tyrosine phosphorylation of the IL-4Ralpha-chain and the transcription factor , STAT6
Rani et al., J Interferon Cytokine Res 2007 : TRAIL was not induced by IFN-beta in mutant cell lines U2A, U3A, U4A, U5A, and U6A, which lack, respectively, IFN regulatory factor-9 (IRF-9), Stat1, Jak1 , IFNAR-2.2, and Stat2, indicating transcription factor IFN stimulated gene factor 3 ( ISGF3 ) was essential for the induction of this gene