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ANG — RAF1

Text-mined interactions from Literome

Smith et al., Endocrinology 1999 (Second Messenger Systems) : Ang II caused a rapid and transient activation of Raf-1 that reached a peak at 5-10 min. Ang II was a potent stimulus of Raf-1 activation with an ED50 of 10 pM and a maximal response at 1 nM, although higher Ang II concentrations elicited a submaximal response
Guillemot et al., J Biol Chem 2000 : Using a pharmacological and a co-transfection approach, we found that p21(ras), Raf-1 , phosphatidylinositol 3-kinase and also the catalytic activity of SHP-2 and its Src homology 2 domains are required for cyclin D1 promoter/reporter gene activation by Ang II through the regulation of MAPK/ERK activity