◀ Back to GP5

CTSG — GP5

Text-mined interactions from Literome

LaRosa et al., J Vasc Surg 1994 (Cardiovascular Diseases) : In a washed platelet system, cathepsin G increased platelet surface expression of P-selectin ( an activation dependent neutrophil binding site ), the glycoprotein IIb/IIIa complex ( fibrinogen receptor ), and glycoprotein IV ( thrombospondin receptor ), and decreased surface expression of glycoprotein Ib ( von Willebrand factor receptor ) to an extent comparable to maximal thrombin
Michelson et al., Blood 1996 : While confirming that both thrombin and neutrophil elastase proteolyse GPV, we show that neutrophil cathepsin G , thrombin receptor activating peptide ( TRAP ), and a combination of ADP and epinephrine can each result in a decrease in the platelet surface expression of GPV by a nonproteolytic mechanism : a cytoskeletal mediated redistribution of platelet surface GPV to the surface connected canalicular system ( SCCS )