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CD2AP — NPHS2

Pathways - manually collected, often from reviews:

• NCI Pathway Database Nephrin/Neph1 signaling in the kidney podocyte: CD2AP (CD2AP) → Nephrin/NEPH1/podocin complex (NPHS1-KIRREL-NPHS2) (modification, collaborate)
  Shih et al., Science 1999*, Schwarz et al., J Clin Invest 2001*, Huber et al., Mol Cell Biol 2003
  Evidence: physical interaction
• NCI Pathway Database Nephrin/Neph1 signaling in the kidney podocyte: CD2AP (CD2AP) → Nephrin/NEPH1/podocin/CD2AP complex (NPHS1-KIRREL-NPHS2-CD2AP) (modification, collaborate)
  Shih et al., Science 1999*, Schwarz et al., J Clin Invest 2001*, Huber et al., Mol Cell Biol 2003
  Evidence: physical interaction
• NCI Pathway Database Nephrin/Neph1 signaling in the kidney podocyte: Nephrin/NEPH1/podocin complex (NPHS1-KIRREL-NPHS2) → Nephrin/NEPH1/podocin/CD2AP complex (NPHS1-KIRREL-NPHS2-CD2AP) (modification, collaborate)
  Shih et al., Science 1999*, Schwarz et al., J Clin Invest 2001*, Huber et al., Mol Cell Biol 2003
  Evidence: physical interaction

Protein-Protein interactions - manually collected from original source literature:

Studies that report less than 10 interactions are marked with *

• IRef Biogrid Interaction: NPHS2 — CD2AP (physical association, affinity chromatography technology) Tossidou et al., J Biol Chem 2010*
• IRef Biogrid Interaction: NPHS2 — CD2AP (physical association, affinity chromatography technology) Schwarz et al., J Clin Invest 2001*
• IRef Biogrid Interaction: NPHS2 — CD2AP (direct interaction, pull down) Schwarz et al., J Clin Invest 2001*
• IRef Hprd Interaction: NPHS2 — CD2AP (in vivo) Schwarz et al., J Clin Invest 2001*
• IRef Hprd Interaction: NPHS2 — CD2AP (in vitro) Schwarz et al., J Clin Invest 2001*
• IRef Ophid Interaction: NPHS2 — CD2AP (aggregation, interologs mapping) Brown et al., Bioinformatics 2005