Gene interactions and pathways from curated databases and text-mining

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IL6 — TNFRSF1B

Text-mined interactions from Literome

Lung et al., Life Sci 2001 : The induction of TNF-R2 gene expression by TNF-alpha was dose dependent and seemed to be unique to TNF-alpha, as interleukin-6 (IL-6) had no significant effect on TNF-R2 expression
Amrani et al., Mol Pharmacol 2001 : Tumor necrosis factor receptor (TNFR) 1, but not TNFR2 , mediates tumor necrosis factor-alpha induced interleukin-6 and RANTES in human airway smooth muscle cells : role of p38 and p42/44 mitogen activated protein kinases
Hu et al., J Investig Dermatol Symp Proc 2007 : This study investigated the effects of murine p75-Fc , a soluble TNF receptor protein, on TNF induced IL-6 production in mice
Hamilton et al., Mol Cancer Res 2011 (Colonic Neoplasms) : TNF receptor (TNFR) 2 expression is increased in inflammatory bowel diseases, the azoxymethane/dextran sodium sulfate ( AOM/DSS ) model of colitis associated cancer, and by combined interleukin (IL) 6 and TNFa ... This study used colon cancer cell lines to test the hypothesis that IL-6 and TNFa induce TNFR2 via STAT3 and/or NF?B
Iwatsuki et al., PloS one 2013 (Hyperalgesia...) : Etanercept reduced expression of interleukin-6 and monocyte chemotactic and activating factor-1 at the crushed sciatic nerve