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INS — NGF
Text-mined interactions from Literome
Hiriart et al., Isr Med Assoc J 2001
:
Moreover, both
NGF and FGF
enhance glucose induced
insulin secretion
Rosenbaum et al., Diabetes 2001
:
We analyzed the
effect of endogenous
NGF on
insulin secretion by incubating islet cells in the presence of an anti-NGF monoclonal antibody for 1 h in different glucose concentrations ... These results suggest that the
effects of
NGF on
insulin secretion are partially mediated by an increase in calcium current through Ca channels
Vidaltamayo et al., FASEB J 2002
:
These data suggest that
NGF could preserve an adequate expression of sodium channels and that impairment of NGF modulation could
lead to deficient
insulin secretion and diabetes mellitus
Bhat et al., J Alzheimers Dis 2002
:
To determine whether these pathways interact from a signalling perspective, we compared the
effects of BAF ( a general caspase inhibitor ), Li+ ( a GSK3beta inhibitor ) and
insulin on
NGF-W induced PC12 cell death
Schreiber et al., J Pediatr Endocrinol 2005
(Hereditary Sensory and Autonomic Neuropathies...) :
We hypothesized that CIPA may represent a natural model for impaired
NGF effect on
insulin secretion in humans ... Additional studies on the clinical significance of
NGF-TrkA effects on
insulin secretion are required
Navarro-Tableros et al., Channels (Austin) 2007
:
NGF increases glucose induced
insulin secretion by modulating electrical activity in adult beta cells
Li et al., Theriogenology 2010
:
Using an immunofluorescent technique, NGF-immunoreactivity was localized to the sperm head and tail, whereas that of TrkA was detected in the acrosomal cap, nucleus, and tail regions When sperm were treated with exogenous NGF, both leptin secretion and sperm viability were increased ( P < 0.05 ) ; moreover, the percentages of late apoptotic and dead sperm were increased ( P < 0.05 ). However,
NGF had no effects on
insulin secretion, mitochondrial activity, intracellular calcium levels, or the acrosome reaction of sperm ( P > 0.05 )
Vidaltamayo et al., Endocrine 1996
:
We studied the
effects of nerve growth factor (NGF), fibroblast growth factor ( FGF ), and dibutyryl-cAMP ( dbcAMP ) on rat pancreatic ß-cell morphology and of
NGF and dbcAMP on
insulin secretion
Sadovnikova et al., Biull Eksp Biol Med 1988
:
The
effects of fibroblast growth factor ( FGF ) and
nerve growth factor (NGF) on DNA synthesis and
insulin secretion were studied in 4-5-day cultures of the isolated neonatal rat islets
Schubert et al., Brain Res 1980
:
Insulin does not, however, alter the morphology of the cells, nor does it
block the morphological response of the cells to
nerve growth factor
González-Hernández et al., Rev Esp Fisiol 1993
:
Insulin and TGF-beta
caused an enhancement of
beta-NGF and c-myc RNA expression
Sher et al., Eur J Cell Biol 1995
(Insulinoma...) :
We also demonstrate that
NGF increases the expression of
insulin and that SgII and insulin are predominantly, but not always, colocalized
Ohmichi et al., J Biol Chem 1994
:
NGF and EGF also
induced the association of Shc proteins with a Grb2 fusion protein or endogenous Grb2, whereas
insulin had no effect
Ang et al., Brain Res Dev Brain Res 1993
:
Insulin , IGF-I or
NGF in the absence of astrocytes did not greatly
increase the neurite growth
Aoyagi et al., Biol Neonate 1997
:
The presence of
NGF ( 100 ng/ml ) during the initial 2-day culture period
increased the
insulin release in the presence of 15 mmol/l glucose and theophylline during the subsequent 24-hour culture period as compared to cells cultured in the absence of NGF