Gene interactions and pathways from curated databases and text-mining

◀ Back to MCM7

E2F2 — MCM7

Pathways - manually collected, often from reviews:

  • WikiPathways Retinoblastoma (RB) in Cancer: Complex of TFDP1-E2F2 → MCM6/MCM7/CDC45/MCM3/MCM4/POLE/ORC1/RPA1/CDK1/CDC7/WEE1 (mim-transcription-translation)

Text-mined interactions from Literome

Bruemmer et al., Exp Cell Res 2003 (Coronary Restenosis...) : In combination, these data demonstrate that the ERK/MAPK signal transduction pathway plays a central role in regulating E2F dependent MCM expression and DNA replication in VSMC
Bruland et al., Br J Cancer 2008 (Anus Neoplasms) : MCM7 is directly regulated by E2F and induced by HPV, and its mRNA was found differentially expressed between the two tumour groups