Gene interactions and pathways from curated databases and text-mining

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FASLG — VIP

Text-mined interactions from Literome

Delgado et al., J Immunol 2000 : VIP/PACAP mediated inhibition of both AICD and FasL expression is mediated through the specific receptors VPAC1 and VPAC2
Delgado et al., J Immunol 2001 (Leukemia L1210...) : A functional study demonstrates that VIP/PACAP inhibit activation induced FasL expression
Ganea et al., Crit Rev Oral Biol Med 2002 (Shock, Septic) : In T-cells expressing specific VIP/PACAP receptors, VIP and PACAP inhibit the expression of FasL through effects on NFkappaB, NFAT, and Egr2/3
Wang et al., Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi 2007 : VIP could regulate the expression pattern of IL-1, IL-6, TGF-beta and FasL by Leydig cells, which may contribute to maintain immune privilege of the testis