Inatomi et al., Int J Mol Med 2006
:
Among the various cytokines and growth factors, interleukin-1beta , tumor necrosis factor-alpha, and EGF strongly induced amphiregulin and epiregulin mRNA expression
Qi et al., J Allergy Clin Immunol 2010
(Asthma) :
Amphiregulin expression by basophils in response to anti-TCR stimulation required IL-3 produced by T cells, and IL-3 alone induced high levels of amphiregulin expression by purified basophils ... IL-3 can induce basophils to express high levels of amphiregulin , which may contribute to tissue remodeling during type 2 immune responses such as asthma