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CRK — WDR61
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Ma et al., Am J Physiol Gastrointest Liver Physiol 2010
:
The increase was reduced by the p38 MAP kinase ( p38 ) inhibitor SB203580, by the cytosolic phospholipase A2 ( cPLA(2) ) inhibitor AACOCF3, and by the lyso-PAF acetyltransferase inhibitor sanguinarin, indicating that capsaicin induced
PAF production may be
mediated by activation of cPLA(2),
p38 , and lyso-PAF acetyltransferase
Zhang et al., J Biol Chem 1999
:
Overexpression of a constitutively active form of Galpha11 ( Galpha11Q209L ) prevented the RGS16 mediated attenuation of p38 activity, suggesting that Galphaq/11 is involved in
PAF activation of
p38