Gene interactions and pathways from curated databases and text-mining

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BCR — PTPN1

Protein-Protein interactions - manually collected from original source literature:

Studies that report less than 10 interactions are marked with *

Text-mined interactions from Literome

Fukada et al., J Biol Chem 2001 : Previously, we have shown that the expression of PTP1B is enhanced by p210 Bcr-Abl and that PTP1B is a specific antagonist of transformation induced by this oncoprotein protein-tyrosine kinase
Alvira et al., J Biol Chem 2011 (Leukemia, Myelogenous, Chronic, BCR-ABL Positive) : Herein we describe a novel mechanism by which the phosphatase activity of PTP1B is required for Bcr-Abl protein stability