Nurse et al., J Allergy Clin Immunol 2000
(Asthma) :
PPD stimulated proliferation, IL-5 release, IFN-gamma release, and the IL-5/IFN-gamma ratio were not significantly different among the groups
Sugata et al., Immunology 2007
:
Dimaprit, clobenpropit and clozapine, which are H4R agonists, dose-dependently blocked both PPD induced interferon-gamma and Cry j1-induced interleukin-5 production by both peripheral blood mononuclear cells ( PBMCs ) and antigen-specific T-cell lines