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CXCL12 — TAC1

Text-mined interactions from Literome

Corcoran et al., J Immunol 2007 : This study investigated the effects of SDF-1alpha on Tac1 expression in the major hemopoietic supporting cells, the bone marrow stroma, and addresses the consequence to hemopoiesis
Corcoran et al., J Mol Endocrinol 2008 : SDF-1alpha regulates Tac1 expression in non-tumorigenic breast cells through a bimodal pattern with repression at high levels through nuclear factor-kappa B (NFkappaB) activation ... Reporter gene assays with the 5 ' flanking region of Tac1 ( exon 1 omitted ) and co-transfection with the repressor of cAMP response element ( CREB ) ( ICER ), and transfection with the CRE sites mutated, verified critical roles for CRE sites in SDF-1alpha mediated Tac1 activation ... In conclusion, this study reports on a non-canonical pathway in Tac1 activation by SDF-1alpha
Corcoran et al., PloS one 2008 (Breast Neoplasms...) : MSC facilitate BCC entry into BM, partly through Tac1 mediated regulation of SDF-1alpha and CXCR4