◀ Back to MYLIP
MYB — MYLIP
Text-mined interactions from Literome
Xiao et al., Cell 2007
:
Combining loss- and gain-of-function gene targeting approaches for miR-150 with conditional and partial ablation of c-Myb, we show that
miR-150 indeed
controls c-Myb expression in vivo in a dose dependent manner over a narrow range of miRNA and c-Myb concentrations and that this dramatically affects lymphocyte development and response
Chung et al., Cancer Biol Ther 2008
:
Moreover, forced overexpression of
miR-15a/16 reduces endogenous
c-Myb levels and compromises Pax5 function
Zhao et al., Blood 2009
(Leukemia) :
Finally, in studies using normal human CD34 ( + ) cells, we showed that
c-Myb and miR-15a expression were inversely correlated in cells undergoing erythroid differentiation, and that overexpression of
miR-15a blocked both erythroid and myeloid colony formation in vitro
Kim et al., Plant Cell Physiol 2008
:
The lack of
miR159 accumulation in ABA treated seeds of cbp20/80 mutants
leads to increased
MYB33 and MYB101 transcript levels, and presumably higher levels of these positive regulators result in ABA hypersensitivity
Zhang et al., Mol Cell 2010
(Atherosclerosis) :
THP-1 derived MVs can enter and deliver miR-150 into human HMEC-1 cells, and elevated exogenous
miR-150 effectively
reduced c-Myb expression and enhanced cell migration in HMEC-1 cells
Imig et al., Nucleic Acids Res 2011
(Epstein-Barr Virus Infections...) :
We show that
c-MYB is targeted by miR-155 and miR-424, that the tumor suppressor SIAH1 is targeted by miR-424, and that c-SKI is potentially
regulated by
miR-155
Zhang et al., Cell Death Differ 2011
(Colorectal Neoplasms) :
In addition,
MYB can
inhibit miR-148a by directly acting on the transcription factor binding site in miR-148a gene and miR-148a can posttranscriptionally silence Bcl-2
Pieczynski et al., Plant Biotechnol J 2013
:
The level of
miR159 was decreased, and the levels of its target mRNAs MYB33 and
MYB101 increased in the transgenic plants subjected to drought
Farhana et al., PloS one 2013
:
Over-expression of
miR-150* also
resulted in diminished levels of
c-Myb and Bcl-2 proteins