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MYLIP — SLC2A4

Text-mined interactions from Literome

Lu et al., Cardiovasc Res 2010 (Diabetes Mellitus, Type 2...) : Loss-of-function studies in vivo, using a synthetic miR-223 inhibitor, confirmed the effect of miR-223 on Glut4 ... These data demonstrate a role for miR-223 in Glut4 regulation and glucose metabolism in the heart, reveal the pleiotropic effects of miRNAs across tissues, and show that miRNAs can upregulate target genes in terminally differentiated cardiomyocytes
Chen et al., Diabetes 2013 (Insulin Resistance...) : GLUT4 is a highly predicted target for miR-93 , while miR-133 and miR-223 have been demonstrated to regulate GLUT4 expression in cardiomyocytes ... Overexpression of miR-93 resulted in downregulation of GLUT4 gene expression in adipocytes through direct targeting of the GLUT4 3'UTR, while inhibition of miR-93 activity led to increased GLUT4 expression