Gene interactions and pathways from curated databases and text-mining

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CFLAR — POLDIP2

Text-mined interactions from Literome

Krysov et al., Mol Cancer Ther 2007 (Lymphoma, Large-Cell, Anaplastic) : Importantly, we show that expression of the caspase-8 inhibitor c-FLIP ( S ) is strongly induced by the CD30 ligand, and that this is dependent on the activation of p38 mitogen activated protein kinase
Lai et al., Anticancer Res 2011 (Carcinoma, Hepatocellular...) : The effect of PEDF on c-FLIP expression was attenuated by p38 kinase inhibitor, but not JNK inhibitor ... PEDF induced p38 signaling causes c-FLIP down-regulation in SK-Hep-1