Gene interactions and pathways from curated databases and text-mining

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MPP1 — TNF

Text-mined interactions from Literome

Glosli et al., Eur J Haematol 1999 : Human TNFalpha binds to and activates the murine p55 receptor, but not the p75 receptor
Chiao et al., AIDS Res Hum Retroviruses 2001 : HIV type 1 Tat inhibits tumor necrosis factor alpha induced repression of tumor necrosis factor receptor p55 and amplifies tumor necrosis factor alpha activity in stably tat transfected HeLa Cells
Rekdal et al., Mediators Inflamm 1994 : The present study was performed to examine whether residues 36-62 of TNFalpha contain the chemotactic domain of TNFalpha, and whether the p55 and p75 TNF receptors are involved in TNFalpha induced chemotaxis
Corti et al., J Immunol Methods 1994 : Moreover, we found that antigenic TNF alpha levels in the presence of p55-sTNF-R ( sTNF-R1 ) measured by different immunoassays were variable, depending on the immunoreagents and incubation time
Peschon et al., J Immunol 1998 (Acute-Phase Reaction...) : In summary, these data help clarify the biologic roles of p55 and p75 in mediating and modulating the biologic activity of TNF and provide genetic evidence for an antagonistic role of p75 in vivo
Lou et al., Eur J Immunol 1998 (Genetic Predisposition to Disease...) : Although the constitutive expression of TNF receptors was comparable on cells from the two origins, TNF induced an up-regulation of both p55 and p75 TNF receptors in CM-S, but not in CM-R brain MVEC