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SHH — WNT7A
Text-mined interactions from Literome
McNeill et al., Mol Cell Neurosci 2012
:
Further validation revealed that the expression of Bok, FoxA1, Sox8 and
Wnt7a was
dependent upon
Sonic Hh (Shh) signaling in the retina and their regulation is under positive and negative controls by Gli2 and Gli3, respectively
Akita et al., Mech Dev 1996
:
Exogenous FGF-4 causes ectopic
Wnt-7a expression and
induces ectopic
Shh
Logan et al., Development 1997
:
Consistent with recent evidence that there is a reciprocal interaction between signalling molecules in the dorsal ectoderm, AER, and zone of polarising activity ( ZPA ), loss of
Wnt7a , Fgf-8 and Fgf-4 expression
leads to a decrease in expression of the signalling molecule
Shh in the ZPA