Gene interactions and pathways from curated databases and text-mining

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GSTA2 — IGF1

Text-mined interactions from Literome

Weil et al., Endocrinology 1999 : The short-term effect of insulin-like growth factor I (IGF-I) on GTH I ( FSH-like ), GTH II ( LH-like ), and GH production by cultured rainbow trout pituitary cells was studied in immature fish of both sexes, at early gametogenesis and in spermiating and periovulatory animals
Huang et al., J Endocrinol 1998 : IGF-I increased both cell content and release of GtH-II in a time- and dose dependent manner ... Comparison of IGF-I and somatostatin ( SRIH-14 ) effects showed that both factors inhibited growth hormone (GH) release but only IGF-I stimulated GtH-II production by eel pituitary cells ... This study demonstrates a specific stimulatory effect of IGF-I on eel GtH-II production, played out directly at the pituitary level