UCSC Genome Browser Gene Interaction Graph

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Gene interactions and pathways from curated databases and text-mining

BioCarta cdk regulation of dna replication: Cyclin E/CDK2/p27 complex (CCNE1-CDK2-CDKN1B) → ORC/CDC6/CDT1/Cyclin E/CDK2/p27 complex (ORC1L-ORC2L-ORC3L-ORC4L-ORC5L-ORC6L-CDC6-CDT1-CCNE1-CDK2-CDKN1B) (modification, collaborate)
BioCarta cdk regulation of dna replication: Cyclin E/CDK2/p27 complex (CCNE1-CDK2-CDKN1B) → ORC/CDC6/CDT1 complex (ORC1L-ORC2L-ORC3L-ORC4L-ORC5L-ORC6L-CDC6-CDT1) (modification, collaborate)
BioCarta cdk regulation of dna replication: ORC/CDC6/CDT1/Cyclin E/CDK2/p27 complex (ORC1L-ORC2L-ORC3L-ORC4L-ORC5L-ORC6L-CDC6-CDT1-CCNE1-CDK2-CDKN1B) → ORC/CDC6/CDT1 complex (ORC1L-ORC2L-ORC3L-ORC4L-ORC5L-ORC6L-CDC6-CDT1) (modification, collaborate)
BioCarta cdk regulation of dna replication: ORC/CDC6/CDT1/Mcm2-7/SCF complex (ORC1L-ORC2L-ORC3L-ORC4L-ORC5L-ORC6L-CDC6-CDT1-MCM2-MCM3-MCM4-MCM5-MCM6-MCM7-KITLG) → ORC/CDC6/CDT1/Cyclin E/CDK2/p27 complex (ORC1L-ORC2L-ORC3L-ORC4L-ORC5L-ORC6L-CDC6-CDT1-CCNE1-CDK2-CDKN1B) (regulation of DNA replication initiation, activates)

Studies that report less than 10 interactions are marked with *

IRef Biogrid Interaction: CCNE1 — CDC6 (direct interaction, enzymatic study) Jiang et al., Proc Natl Acad Sci U S A 1999 *
STRING interaction: CCNE1 — CDC6 (interaction, mapped from kegg_pathways)
STRING interaction: CDC6 — CCNE1 (interaction, mapped from kegg_pathways)