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POLI — SP1

Text-mined interactions from Literome

Zhu et al., Environ Toxicol Pharmacol 2010 : However, the promoter with the Sp1 site mutation had no response to MNNG treatment, suggesting that Sp1 plays an important role in the transcriptional regulation of the POLI gene stimulated by MNNG
Zhou et al., Cancer Sci 2012 (Carcinoma, Squamous Cell...) : We observed that the binding affinity of Sp1 to the POLI promoter was significantly increased in cancerous tissues and that Sp1 activated POLI gene transcription in cultured cell lines ... The present study demonstrates overexpression of the TLS genes in esophageal carcinoma and identifies a key role for Sp1 in upregulating POLI gene expression