Zhao et al., J Pharm Pharmacol 2007
(Osteoporosis) :
The results indicate that GLP can effectively promote the proliferation and differentiation of osteoblasts and regulate their OPG/RANKL expression, while the effects may be mediated via the p38 MAPK pathway
Huang et al., Nan Fang Yi Ke Da Xue Xue Bao 2008
(MAP Kinase Signaling System) :
GLP promotes the proliferation and differentiation of osteoblasts and regulates OPG/RANKL expressions in vitro, which are mediated probably via the p38 MAPK pathway
Nuche-Berenguer et al., Calcif Tissue Int 2009
(Bone Resorption...) :
Bone OC, osteoprotegerin (OPG) and RANKL mRNA were lower in T2D and IR ; GLP-1 increased OC and OPG in all groups and RANKL in T2D