◀ Back to VWF

GP6 — VWF

Text-mined interactions from Literome

Wang et al., Thromb Haemost 2004 (Inflammation...) : The results of this study can be summarized as follows : ( 1 ) moderate exercise was associated with lower extents of shear induced platelet adhesion and aggregation, binding of von Willbrand factor (vWF) to platelets, and glyco-protein IIb/IIIa activation and P-selectin expression on platelet than at rest ; ( 2 ) the velocity and percentage of rolling PMNs increased while the number of PMNs remaining bound to surface-adherent platelets decreased after moderate exercise ; ( 3 ) although treating the PMNs with oxidized-low density lipoprotein ( Ox-LDL ) enhanced PMNs interaction with surface-adherent platelets, moderate exercise suppressed the enhancement of platelet-PMN interaction by Ox-LDL ; ( 4 ) moderate exercise decreased platelet [ Ca ( 2+ ) ] ( i ) elevation induced by ADP and platelet [ Ca ( 2+ ) ] ( i ) levels mediated by PMN and Ox-LDL treated PMN ; and ( 5 ) plasma and PMN derived nitric oxide metabolites and plasma vWF antigen and activity increased after moderate exercise, whereas plasma and platelet derived soluble P-selectin levels remained unchanged in response to exercise
Santoro et al., Blood 1989 : In contrast to the inhibition of platelet adhesion to von Willebrand factor mediated by the glycoprotein IIb-IIIa complex, gangliosides had no detectable effect on the ristocetin dependent adhesion of platelets to von Willebrand factor mediated by glycoprotein Ib