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IL1A — NPY
Text-mined interactions from Literome
Ferreira et al., J Biol Chem 2010
(Inflammation) :
Given the modulatory role of neuropeptide Y (NPY) in the immune system, we investigated the
effect of
NPY on the production of NO and
IL-1ß in microglia ... Moreover,
NPY acting through Y ( 1 ) receptor
inhibited LPS stimulated release of
IL-1ß , inhibiting NO synthesis
Zhou et al., J Neuroimmunol 2013
(MAP Kinase Signaling System) :
In the present work, we have evaluated the
effects of
NPY on the release of TNF-a,
IL-1ß , IL-6 and HMGB1 mediators in peritoneal macrophages ... Our results demonstrate for the first time that
NPY can directly
induce active HMGB1 release and cytoplasmic translocation, while the production of TNF-a,
IL-1ß and IL-6 is not affected