Gene interactions and pathways from curated databases and text-mining

◀ Back to CXCL12

CA2 — CXCL12

Text-mined interactions from Literome

Cabrera et al., AIDS Res Hum Retroviruses 2000 (Calcium Signaling) : Both compounds inhibited the binding of a monoclonal antibody ( 12G5 ) directed to CXCR4 as well as the intracellular Ca2+ signal induced by the chemokine SDF-1alpha on CXCR4+ cells, suggesting that aminoglycoside-arginine conjugates interact with CXCR4, the coreceptor used by T-tropic, X4 strains of HIV-1
Princen et al., Cytometry A 2003 (Calcium Signaling) : Evaluation of SDF-1/CXCR4 induced Ca2+ signaling by fluorometric imaging plate reader ( FLIPR ) and flow cytometry
Tanaka et al., Int J Oncol 2006 : The DCs generated in this study mobilized Ca2+ in response to CCL21/6Ckine and SDF-1 , but only marginally did so to Mip-1alpha
Massa et al., Ann N Y Acad Sci 2006 (Adenoma...) : SDF-1 increased cytosolic [ Ca2+ ] and activated Pyk2, ERK1/2, and BKCa channels ... We report that the inhibition of [ Ca2+ ] i increase or the blockade of BKCa channel activity did not affect ERK1/2 activation by SDF-1 ; Pyk2 activation was purely Ca2+ dependent, not involving ERK1/2 or BKCa channels ; and BKCa channel activity was antagonized by Pyk2 but not by ERK1/2 inhibitors
McCord et al., DNA Cell Biol 2007 : Further, it was demonstrated that BCM enhanced CXCL8 production and HUVEC proliferation in a Ca2+ dependent manner
Bleul et al., Nature 1996 : SDF-1 induced an increase in intracellular free Ca2+ and chemotaxis in CXCR-4 transfected cells
Nagasawa et al., Proc Natl Acad Sci U S A 1996 : Murine PBSF/SDF-1 induced an increase in intracellular free Ca2+ in DW34 cells and PB-CKR transfected Chinese hamster ovary ( CHO ) cells, suggesting that PB-CKR is a functional receptor for murine PBSF/SDF-1
Proost et al., FEBS Lett 1998 : However, SDF-1alpha ( 3-68 ) still desensitized the SDF-1alpha ( 1-68 ) -induced Ca2+ response