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CA2 — CXCL12
Text-mined interactions from Literome
Cabrera et al., AIDS Res Hum Retroviruses 2000
(Calcium Signaling) :
Both compounds inhibited the binding of a monoclonal antibody ( 12G5 ) directed to CXCR4 as well as the intracellular
Ca2+ signal
induced by the chemokine
SDF-1alpha on CXCR4+ cells, suggesting that aminoglycoside-arginine conjugates interact with CXCR4, the coreceptor used by T-tropic, X4 strains of HIV-1
Princen et al., Cytometry A 2003
(Calcium Signaling) :
Evaluation of
SDF-1/CXCR4 induced
Ca2+ signaling by fluorometric imaging plate reader ( FLIPR ) and flow cytometry
Tanaka et al., Int J Oncol 2006
:
The DCs generated in this study mobilized
Ca2+ in
response to CCL21/6Ckine and
SDF-1 , but only marginally did so to Mip-1alpha
Massa et al., Ann N Y Acad Sci 2006
(Adenoma...) :
SDF-1 increased cytosolic [
Ca2+ ] and activated Pyk2, ERK1/2, and BKCa channels ... We report that the inhibition of [
Ca2+ ] i increase or the blockade of BKCa channel activity did not
affect ERK1/2 activation by
SDF-1 ; Pyk2 activation was purely Ca2+ dependent, not involving ERK1/2 or BKCa channels ; and BKCa channel activity was antagonized by Pyk2 but not by ERK1/2 inhibitors
McCord et al., DNA Cell Biol 2007
:
Further, it was demonstrated that BCM enhanced
CXCL8 production and HUVEC proliferation in a
Ca2+ dependent manner
Bleul et al., Nature 1996
:
SDF-1 induced an increase in intracellular free
Ca2+ and chemotaxis in CXCR-4 transfected cells
Nagasawa et al., Proc Natl Acad Sci U S A 1996
:
Murine
PBSF/SDF-1 induced an increase in intracellular free
Ca2+ in DW34 cells and PB-CKR transfected Chinese hamster ovary ( CHO ) cells, suggesting that PB-CKR is a functional receptor for murine PBSF/SDF-1
Proost et al., FEBS Lett 1998
:
However, SDF-1alpha ( 3-68 ) still desensitized the
SDF-1alpha ( 1-68 ) -induced
Ca2+ response