◀ Back to CDK1

CDK1 — MAP2K1

Pathways - manually collected, often from reviews:

• Reactome Reaction: MAP2K1 → CDK1 (reaction)

Text-mined interactions from Literome

Kivinen et al., Oncogene 1999 (MAP Kinase Signaling System) : p21Cip1/Waf1 cyclin dependent kinase inhibitor ( p21 ) is inducible by Raf and mitogen activated protein kinase kinase ( MAPKK ), but the level of regulation is unknown
Minelli et al., Peptides 2006 : It greatly enhances the phosphorylation of hsp27, alpha-B-crystallin, Cdc2 , and p-38 MAPK, whereas it decreases the phosphorylation of MEK1 , Cav 2, GSK3a, PKB/Akt, PKCdelta, PKCgamma, and Erk2
Pérez-Hidalgo et al., Cell cycle (Georgetown, Tex.) 2008 : Using ectopic overexpression of mek1 ( + ) as a tool to induce in vivo activation of Mek1, we find that Mek1 promotes cytoplasmic accumulation of Cdc25 and results in prolonged phosphorylation of Cdc2 at tyrosine 15