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APOA4 — APOB
Pathways - manually collected, often from reviews:
-
Reactome Reaction:
APOA4
→
APOB
(indirect_complex)
Nayak et al., J Lipid Res 2001*, Hussain et al., J Lipid Res 2003*, Jones et al., Nat Genet 2003*, Gordon et al., Trends Cell Biol 1995*, During et al., J Lipid Res 2007*
-
Reactome Reaction:
APOA4
→
APOB
(reaction)
Hussain et al., J Lipid Res 2003*, Gordon et al., Trends Cell Biol 1995*
Text-mined interactions from Literome
Foth et al., Zentralbl Gynakol 2000
:
Apolipoprotein B, cholesterol and
LDL-Cholesterol decreased,
apolipoprotein A 1
increased
Sun et al., J Biol Chem 2002
(Arteriosclerosis...) :
Lipoprotein(a) enhances advanced atherosclerosis and vascular calcification in WHHL transgenic rabbits expressing human
apolipoprotein ( a )
Scanu et al., Ann Epidemiol 1992
(Arteriosclerosis...) :
The role that lipoprotein ( a ) size and density heterogeneity and
apolipoprotein ( a ) polymorphism might
play in the intima accumulation of
apolipoprotein B is not established
Black et al., Biochem J 1992
:
Apo B may be specifically
down-regulated by the
chylomicron secretory blockade induced by Pluronic L-81
Matthews et al., N Engl J Med 1989
(Coronary Disease) :
In menopausal women who received hormone-replacement therapy, HDL and
LDL cholesterol levels did not change, but the levels of triglycerides ( +0.42 vs. -0.04 mmol per liter ; P less than 0.001 ),
apolipoprotein A-I ( +0.18 vs. +0.03 g per liter ; P less than 0.01 ), and apolipoprotein A-II ( +0.05 vs. -0.03 g per liter ; P less than 0.05 )
increased as compared with premenopausal controls
Rovamo et al., Pediatr Res 1985
(Gastrointestinal Diseases) :
Serum apolipoprotein A-I concentrations were unaltered,
apolipoprotein A-II underwent a transient increase, and
apolipoprotein B increased monotonically during parenteral nutrition
Levy et al., FEBS Lett 1996
:
Adding insulin ( 3 mU ) to the serum-free medium of cultured jejunal explants from human fetuses ( 17-20 weeks ) reduced triglyceride and
chylomicron production and
inhibited apo B-48 and
apo B-100 secretion
Taggart et al., Diabet Med 1997
(Diabetes Mellitus, Type 2) :
The postprandial
chylomicron apolipoprotein B48 response of both diabetic and control subjects to the cholesterol meal was less than to the cholesterol-free meal ( p < 0.001 )